Yay! One reason holding me to using FireFox on Mac was that I rely heavily on Scribefire which was not really working on Safari. I am using it now on Safari 5. It seems ok but, first blush it doesn't seem quite as nice as on Firefox. But at least it gives me a chance to try starting to use Safari to see if it's all it's cracked up to be! Check out Scribefire, on Firefox or Safari (and I guess Chrome.)
Chrome: I just can't get used to it's weird tab user interface. There goes Google again, reinventing the wheel. Gmail doesn't have folders, it has tags. And now Chrome has funny tabs instead of ones that look 'normal'